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Tocris Bioscience™ PSB 12379
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Catalog No. 608310
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60-831-0 10 mg
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Catalog No. 60-831-0 Supplier Tocris Bioscience™ Supplier No. 6083/10
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Ecto-5'-nucleotidase (CD73) inhibitor

PSB 12379 is a selective high affinity ecto-5'-nucleotidase/CD73 inhibitor (Ki values are 2.21 and 9.03 nM at human and rat CD73, respectively). Blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. Exhibits selectivity over other ecto-nucleotidases and ADP-activated P2Y receptors tested.

Specifications

Chemical Name or Material N6-Benzyl-α,β-methyleneadenosine 5′-diphosphate disodium salt
Assay Percent Range >98%
Quantity 10 mg
Molecular Formula C18H21N5Na2O9P2
Formula Weight Observed MW: 559.31
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