Invitrogen™ PSCA Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA543622

Catalog No. PIMA543622

Description

PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in approximately40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

Specifications

• Antigen: PSCA
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: O43653
• Gene Symbols: PSCA
• Immunogen: Leu13-Ser86 with N-terminal His Tag.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Western Blot
• Clone: C1
• Conjugate: Unconjugated
• Gene: PSCA
• Gene Alias: 2210408B04Rik; caldesmon; CDM; HCAD; H-CAD; LCAD; L-CAD; NAG22; PRO232; prostate stem cell antigen; PSCA; UNQ206; UNQ206/PRO232
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 8000
• Content And Storage: -20°C
• Form: Liquid