Invitrogen™ PSCA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115799

Catalog No. PIPA5115799

Description

Antibody detects endogenous levels of total Prostate Stem Cell Antigen.

PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in approximately40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

Specifications

• Antigen: PSCA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSCA
• Gene Alias: 2210408B04Rik; caldesmon; CDM; HCAD; H-CAD; LCAD; L-CAD; NAG22; PRO232; prostate stem cell antigen; PSCA; UNQ206; UNQ206/PRO232
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 680210, 72373, 8000
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O43653, P57096
• Gene Symbols: PSCA
• Immunogen: A synthesized peptide derived from human PSCA(Accession O43653), corresponding to amino acid residues A51-Q101.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov