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Tocris Bioscience™ PSEM 308 hydrochloride

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Quantity:
5 mg
25 mg
Description
PSEM 308 hydrochloride is a PSAM (pharmacologically selective actuator module) agonist. Activates PSAML141F-GlyR chimeric ion channels. Inhibits activity of neurons expressing PSAML141F-GlyR in vivo and activates locus coeruleus noradrenergic neurons expressing PSAML141F,Y115F-5-HT3 ion channels.
Recommended concentration for use in mice is 5 mg/kg or lower.
Plasmid vectors for the transfection of cells with PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 are available from Addgene.
Specifications
Specifications
Chemical Name or Material | 5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride |
Quantity | 25 mg |
Target | Pharmacologically Selective Effector Molecules/PSEM |
Molecular Formula | C17H21N3.HCl |
Formula Weight | 303.83 |
Purity | 98% |
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