Invitrogen™ PSG1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542144

Catalog No. PIPA542144

Description

Peptide sequence: SGRETAYSNA SLLIQNVTRE DAGSYTLHII KGDDGTRGVT GRFTFTLHLE Sequence homology: Human: 100%.

Human pregnancy-specific glycoproteins (PSG), are a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarcinoma). They represent the most abundant fetal protein in the maternal blood at term. The eleven human PSG genes (PSG1-PSG11) form together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes the CEACAM gene family. PSG stimulates secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17. PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection.

Specifications

• Antigen: PSG1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSG1
• Gene Alias: B1G1; CD66 antigen-like family member F; CD66f; DHFRP2; Fetal liver non-specific cross-reactive antigen 1/2; FLJ90598; FLJ90654; FL-NCA-1/2; PBG1; pregnancy specific beta-1-glycoprotein 1; pregnancy-specific B-1 glycoprotein; pregnancy-specific beta-1 glycoprotein C/D; Pregnancy-specific beta-1-glycoprotein 1; PS-beta-C/D; PS-beta-G-1; PSBG1; PSBG-1; PSG 1; PSG IIA-d; PSG1; PSG-1d; PSG95; PSGGA; PSGIIA; PSGIIA-a; PSGIIA-b; PSGIIA-c; SP 1; SP1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5669
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P11464
• Gene Symbols: PSG1
• Immunogen: Synthetic peptide directed towards the N-terminal of human PSG1 (aa 96-145).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG