Invitrogen™ PSKH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553278

Catalog No. PIPA553278

Description

Immunogen sequence: SGFLPFDDES QTRLYRKILK GKYNYTGEPW PSISHLAKDF IDKLLILEAG HRMSAGQALD HPWVITMAAG SSMKNLQRAI SRNLMQRASP HSQSPGSAQS SKSHYSHKSR Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 62%.

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. PSKH2 (protein serine kinase H2) is a 385 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. Containing one protein kinase domain, PSKH2 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Specifications

• Antigen: PSKH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSKH2
• Gene Alias: protein serine kinase H2; PSKH2; PSK-H2; serine/threonine kinase PSKH2; serine/threonine-protein kinase H2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 85481
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96QS6
• Gene Symbols: PSKH2
• Immunogen: Recombinant protein corresponding to Human PSKH2. Recombinant protein control fragment (Product #RP-91450).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov