Invitrogen™ PSMA6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120222

Catalog No. PIPA5120222

Description

Positive test controls include: HepG2, HeLa, A-549, COS-7, PC-12, MCF7, NCI-H460, A375, Mouse skeletal muscle. The target is usually found in the following locations: Cytoplasm, Nucleus, P-body. Immunogen sequence: MSRGSSAGFD RHITIFSPEG RLYQVEYAFK AINQGGLTSV AVRGKDCAVI VTQKKVPDKL LDSSTVTHLF KITENIGCVM TGMTADSRSQ VQRARYEAAN WKYKYGYEIP VDMLCKRIAD ISQVYTQNAE MRPLGCCMIL IGIDEEQGPQ VYKCDPAGYY CGFKATAAGV KQTESTSFLE KKVKKKFDWT FEQTVETAIT CLSTVLSIDF KPSEIEVGVV TVENPKFRIL TEAEIDAHLV ALAERD.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.

Specifications

• Antigen: PSMA6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSMA6
• Gene Alias: 27 kDa prosomal protein; EGK_18113; IOTA; Macropain iota chain; macropain subunit iota; MGC22756; MGC2333; MGC23846; multicatalytic endopeptidase complex iota chain; p27K; PROS 27; PROS27; PROS-27; prosomal P27K protein; proteasome (prosome, macropain) subunit, alpha type 6; proteasome (prosome, macropain) subunit, alpha type, 6; proteasome 20S subunit alpha 6; proteasome alpha 6 subunit; proteasome iota chain; proteasome subunit alpha 6; proteasome subunit alpha type-6; proteasome subunit iota; PSA6; PSMA 6; PSMA6; testicular secretory protein Li 44
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26443, 29673, 5687
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P60900, P60901, Q9QUM9
• Gene Symbols: PSMA6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PSMA6 (NP_002782.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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