Invitrogen™ PSMA6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521636

Catalog No. PIPA521636

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Raji, mouse brain. Predicted reactivity: Mouse (99%), Rat (100%), Xenopus laevis (89%), Pig (99%), Chicken (96%), Sheep (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.

Specifications

• Antigen: PSMA6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSMA6
• Gene Alias: 27 kDa prosomal protein; EGK_18113; IOTA; Macropain iota chain; macropain subunit iota; MGC22756; MGC2333; MGC23846; multicatalytic endopeptidase complex iota chain; p27K; PROS 27; PROS27; PROS-27; prosomal P27K protein; proteasome (prosome, macropain) subunit, alpha type 6; proteasome (prosome, macropain) subunit, alpha type, 6; proteasome 20S subunit alpha 6; proteasome alpha 6 subunit; proteasome iota chain; proteasome subunit alpha 6; proteasome subunit alpha type-6; proteasome subunit iota; PSA6; PSMA 6; PSMA6; testicular secretory protein Li 44
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26443, 5687
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P60900, Q9QUM9
• Gene Symbols: PSMA6
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PSMA6. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov