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Invitrogen™ PSMA8 Polyclonal Antibody
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Catalog No. PIPA589783
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100 μL
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PIPA589783 100 μL
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Catalog No. PIPA589783 Supplier Invitrogen™ Supplier No. PA589783
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MASRYDRAIT VFSPDGHLFQ VEYAQEAVKK GSTAVGIRGT NIVVLGVEKK SVAKLQDERT VRKICALDDH VCMAFAVLTI FIGLTADARV VINRARVECQ SHKLTVEDPV TVEYITRFIA TLKQKYTQSN GRRPFGISAL IVGFDDDGIS RLYQTDPSGT YHAWKANAIG RSAKTVREFL EKNYTEDAIA SDSEAIKLAI KALLEVVQSG GKNIELAIIR RNQPLKMFSA KEVELYVTEI; Positive Samples: K-562, Mouse thymus, Mouse testis, Rat testis; Cellular Location: Cytoplasm, Nucleus.

Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complexe that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSMA8
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene PSMA8
Gene Accession No. Q8TAA3, Q9CWH6
Gene Alias 2410072D24Rik; proteasome (prosome, macropain) subunit, alpha type, 8; proteasome 20S subunit alpha 8; proteasome alpha 8 subunit; proteasome subunit alpha 8; proteasome subunit alpha type 7; proteasome subunit alpha type 7-like protein variant 1; proteasome subunit alpha type-7-like; Proteasome subunit alpha-type 7-like; Proteasome subunit alpha-type 8; psma7; PSMA7L; PSMA8; RGD1311659; wu:fk28c01; zgc:77139
Gene Symbols PSMA8
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PSMA8 (NP_6532632).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 143471, 364814, 73677
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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