Invitrogen™ PSMB3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560115

Catalog No. PIPA560115

Description

Immunogen sequence: LYEKRFGPYY TEPVIAGLDP KTFKPFICSL DLIGCPMVTD DFVVSGTCAE QMYGMCESLW EPNMDPDHLF ETISQAMLNA VDRD Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.

Specifications

• Antigen: PSMB3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSMB3
• Gene Alias: AL033320; C10-II; HC10-II; MGC4147; proteasome (prosome, macropain) subunit, beta type 3; proteasome (prosome, macropain) subunit, beta type, 3; proteasome beta 3 subunit; proteasome chain 13; Proteasome component C10-II; proteasome subunit beta 3; proteasome subunit beta type-3; Proteasome theta chain; PSMB3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5691
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P49720
• Gene Symbols: PSMB3
• Immunogen: Recombinant protein corresponding to Human PSMB3. Recombinant protein control fragment (Product #RP-100106).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov