PSMB7 Monoclonal Antibody (OTI4G9), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-5094	100 μL
50-254-0353	30 μL

Catalog No. 50-167-5094 Supplier OriGene Supplier No. TA504383

Description

Mouse Monoclonal Antibody

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).

Specifications

• Antigen: PSMB7
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: OTI4G9
• Concentration: 0.59 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: PSMB7
• Gene Accession No.: P70195, Q99436, Q9JHW0
• Gene Alias: Z
• Gene Symbols: PSMB7
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 58-277 of human PSMB7 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100686423, 19177, 5695, 85492
• Target Species: Canine, Human, Mouse, Rat
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1