PSMB9 Monoclonal Antibody (OTI3H1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA504388

Catalog No. 50-167-5097

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.

Specifications

• Antigen: PSMB9
• Classification: Monoclonal
• Concentration: 1.2 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P28065
• Gene Symbols: PSMB9
• Immunogen: Human recombit protein fragment corresponding to amino acids 21-219 of human PSMB9 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3H1
• Conjugate: Unconjugated
• Gene: PSMB9
• Gene Alias: LMP2, PSMB6i, RING12, beta1i
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5698
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid