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PSMC3 Mouse anti-Canine, Human, Clone: OTI9F3, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA500922

Catalog No. 50-167-2063


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Description

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.
Specifications

Specifications

PSMC3
Monoclonal
0.58 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P17980
TBP1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
475980, 5702
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI9F3
Unconjugated
PSMC3
Liquid
PSMC3
Full length human recombit protein of human PSMC3 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human
Documents
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