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Invitrogen™ PSMC3IP Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA543070
Description
Peptide sequence: RLKNIKAATN HVTPEEKEQV YRERQKYCKE WRKRKRMATE LSDAILEGYP Sequence homology: Cow: 93%; Dog: 100%; Goat: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 93%.
PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
Specifications
PSMC3IP | |
Polyclonal | |
Unconjugated | |
PSMC3IP | |
C79099; DBD-interacting; Gt198; Homologous-pairing protein 2 homolog; homologous-pairing protein 2 homolog-like; Hop2; HUMGT198A; Nuclear receptor coactivator GT198; ODG3; proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein; proteasome 26S ATPase subunit 3-interacting protein; PSMC3 interacting protein; PSMC3-interacting protein; PSMC3IP; Tat-binding protein 1-interacting protein; TBP-1-interacting protein; Tbpip | |
Rabbit | |
Protein A | |
RUO | |
29893 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide | |
Q9P2W1 | |
PSMC3IP | |
Synthetic peptide directed towards the middle region of human PSMC3IP. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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