Invitrogen™ PSMC3IP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA543070

Catalog No. PIPA543070

Description

Peptide sequence: RLKNIKAATN HVTPEEKEQV YRERQKYCKE WRKRKRMATE LSDAILEGYP Sequence homology: Cow: 93%; Dog: 100%; Goat: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 93%.

PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.

Specifications

• Antigen: PSMC3IP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSMC3IP
• Gene Alias: C79099; DBD-interacting; Gt198; Homologous-pairing protein 2 homolog; homologous-pairing protein 2 homolog-like; Hop2; HUMGT198A; Nuclear receptor coactivator GT198; ODG3; proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein; proteasome 26S ATPase subunit 3-interacting protein; PSMC3 interacting protein; PSMC3-interacting protein; PSMC3IP; Tat-binding protein 1-interacting protein; TBP-1-interacting protein; Tbpip
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 29893
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9P2W1
• Gene Symbols: PSMC3IP
• Immunogen: Synthetic peptide directed towards the middle region of human PSMC3IP.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov