Invitrogen™ PSMC3IP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100560

Catalog No. PIPA5100560

Description

Antibody detects endogenous levels of total HOP2.

PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.

Specifications

• Antigen: PSMC3IP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSMC3IP
• Gene Alias: C79099; DBD-interacting; Gt198; Homologous-pairing protein 2 homolog; homologous-pairing protein 2 homolog-like; Hop2; HUMGT198A; Nuclear receptor coactivator GT198; ODG3; proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein; proteasome 26S ATPase subunit 3-interacting protein; PSMC3 interacting protein; PSMC3-interacting protein; PSMC3IP; Tat-binding protein 1-interacting protein; TBP-1-interacting protein; Tbpip
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29893
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9P2W1
• Gene Symbols: PSMC3IP
• Immunogen: A synthesized peptide derived from human PSMC3IP(Accession Q9P2W1), corresponding to amino acid residues R166-D216.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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