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Invitrogen™ PSMC3IP Polyclonal Antibody
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Catalog No. PIPA5100560
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100 μL
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PIPA5100560 100 μL
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Catalog No. PIPA5100560 Supplier Invitrogen™ Supplier No. PA5100560
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total HOP2.

PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSMC3IP
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PSMC3IP
Gene Accession No. Q9P2W1
Gene Alias C79099; DBD-interacting; Gt198; Homologous-pairing protein 2 homolog; homologous-pairing protein 2 homolog-like; Hop2; HUMGT198A; Nuclear receptor coactivator GT198; ODG3; proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein; proteasome 26S ATPase subunit 3-interacting protein; PSMC3 interacting protein; PSMC3-interacting protein; PSMC3IP; Tat-binding protein 1-interacting protein; TBP-1-interacting protein; Tbpip
Gene Symbols PSMC3IP
Host Species Rabbit
Immunogen A synthesized peptide derived from human PSMC3IP(Accession Q9P2W1), corresponding to amino acid residues R166-D216.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29893
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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