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Invitrogen™ PSMD10 Monoclonal Antibody (OTI3F6)
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Catalog No. PIMA525016
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100 μL
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PIMA525016 100 μL
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Catalog No. PIMA525016 Supplier Invitrogen™ Supplier No. MA525016
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Description

Mouse Monoclonal Antibody

PSMD10 Monoclonal Antibody for Western Blot, Flow

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSMD10
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone OTI3F6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PSMD10
Gene Accession No. O75832
Gene Alias 26S proteasome non-ATPase regulatory subunit 10; 26S proteasome regulatory subunit p28; ankyrin repeat protein; AW554874; dJ889N15.2; Gankyrin; hepatocellular carcinoma-associated protein p28-II; p28; p28(GANK); p28Gank; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10; proteasome 26S subunit, non-ATPase 10; proteasome subunit p28; proteosome (prosome, macropain) 26S subunit, non-ATPase, 10; proteosome subunit p28; PSMD10
Gene Symbols PSMD10
Host Species Mouse
Immunogen Full length human recombinant protein of PSMD10 produced in HEK293T cell.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5716
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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