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Invitrogen™ PSMD11 Polyclonal Antibody
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Catalog No. PIPA5101344
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PIPA5101344 100 μL
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Catalog No. PIPA5101344 Supplier Invitrogen™ Supplier No. PA5101344
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total PSMD11.

The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSMD11
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Psmd11
Gene Accession No. O00231, Q8BG32
Gene Alias 1700089D09Rik; 1810019E17Rik; 2610024G20Rik; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit 9; 26S proteasome regulatory subunit p44.5; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 2810055C24Rik; C78232; p44.5; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; proteasome 26S subunit, non-ATPase 11; Psmd11; Rpn6; S9
Gene Symbols Psmd11
Host Species Rabbit
Immunogen A synthesized peptide derived from human PSMD11(Accession O00231), corresponding to amino acid residues S272-H322.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5717, 69077
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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