Invitrogen™ PSMD11 Polyclonal Antibody

Catalog No.	Quantity
FEPA5144656	100 μL

Catalog No. FEPA5144656 Supplier Invitrogen™ Supplier No. PA5144656

Description

Rabbit Polyclonal Antibody

Positive control: 293T cell lysate, HepG2 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, PC-3 cell lysate, Hela cell lysate, mouse testis tissue lysate, rat testis tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, mouse testis tissue, NIH/3T3. Predicted band size: 47 kDa Subcellular Location: Cytoplasm, Nucleus.

The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.

Specifications

• Antigen: PSMD11
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: Psmd11
• Gene Accession No.: F1LMZ8, O00231, Q8BG32
• Gene Alias: 1700089D09Rik; 1810019E17Rik; 2610024G20Rik; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit 9; 26S proteasome regulatory subunit p44.5; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 2810055C24Rik; C78232; p44.5; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; proteasome 26S subunit, non-ATPase 11; Psmd11; Rpn6; S9
• Gene Symbols: Psmd11
• Host Species: Rabbit
• Immunogen: Synthetic peptide within human PSMD11 aa 200-500.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 303353, 5717, 69077
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG