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Invitrogen™ PSMD11 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA566921
Description
Immunogen sequence: AAVVEFQRAQS LLSTDREASI DILHSIVKRD IQENDEEAVQ VKEQSILELG SLLAKTGQAA ELGGLLKY Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.
Specifications
PSMD11 | |
Polyclonal | |
Unconjugated | |
Psmd11 | |
1700089D09Rik; 1810019E17Rik; 2610024G20Rik; 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit 9; 26S proteasome regulatory subunit p44.5; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; 2810055C24Rik; C78232; p44.5; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; proteasome 26S subunit, non-ATPase 11; Psmd11; Rpn6; S9 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
5717 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.05 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
O00231 | |
Psmd11 | |
Recombinant Human PSMD11. Recombinant protein control fragment (Product #RP-105425). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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