PSMD3 Monoclonal Antibody (OTI2A2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA504337

Catalog No. 50-167-5055

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.

Specifications

• Antigen: PSMD3
• Classification: Monoclonal
• Concentration: 0.95 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O43242, P14685
• Gene Symbols: Psmd3
• Immunogen: Full length human recombit protein of human PSMD3 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Western Blot
• Clone: OTI2A2
• Conjugate: Unconjugated
• Gene: PSMD3
• Gene Alias: P58, RPN3, S3, TSTA2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22123, 287670, 491018, 5709
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid