Invitrogen™ PSMD3 Monoclonal Antibody (OTI2C2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA525873

Catalog No. PIMA525873

Description

PSMD3 Monoclonal Antibody for Western Blot, ICC/IF, Flow

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.

Specifications

• Antigen: PSMD3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43242
• Gene Symbols: PSMD3
• Immunogen: Full length human recombinant protein of PSMD3 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: OTI2C2
• Conjugate: Unconjugated
• Gene: PSMD3
• Gene Alias: 26S proteasome non-ATPase regulatory subunit 3; 26S proteasome regulatory subunit RPN3; 26S proteasome regulatory subunit S3; AI255837; AntP91a; D11Bwg1349e; EGK_08646; P58; P91a; proteasome (prosome, macropain) 26S subunit, non-ATPase, 3; proteasome 26S non-ATPase subunit 3; proteasome 26S subunit, non-ATPase 3; proteasome subunit p58; Psd3; Psmd3; RPN3; S3; tissue specific transplantation antigen 2; tissue specific transplantation antigen P91A; transplantation antigen P91A; TSTA2; Tstap91a; Tum-P91A antigen
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5709
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid