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PSMD5/26S Proteasome Subunit S5B Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304999A

Encompass_Preferred

Catalog No. 50-156-9240


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.
Specifications

Specifications

PSMD5/26S Proteasome Subunit S5B
Polyclonal
Unconjugated
PSMD5
RP11-27I1.5, KIAA0072, MGC23145, S5B
Rabbit
Antigen affinity chromatography
RUO
5711
4° C
Liquid
Immunoprecipitation, Western Blot
1 mg/ml
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Q16401
PSMD5
Between 325 and 375
100 μL
Primary
Human
Antibody
IgG
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