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Invitrogen™ PSMD5 Polyclonal Antibody
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Catalog No. PIPA530137
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100 μL
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PIPA530137 100 μL
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Catalog No. PIPA530137 Supplier Invitrogen™ Supplier No. PA530137
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain. Predicted reactivity: Mouse (91%), Rat (88%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSMD5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene PSMD5
Gene Accession No. Q16401, Q8BJY1
Gene Alias 1500032A03Rik; 26S protease subunit S5 basic; 26S proteasome non-ATPase regulatory subunit 5; 26S proteasome subunit S5B; AW475925; KIAA0072; MGC23145; mKIAA0072; proteasome (prosome, macropain) 26S subunit, non-ATPase, 5; proteasome 26S subunit, non-ATPase 5; PSMD5; RP11-27I1.5; S5b; W91691
Gene Symbols PSMD5
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PSMD5. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5711, 66998
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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