Invitrogen™ PSMD8 Polyclonal Antibody

Catalog No.	Quantity
PIPA5144028	100 μg

Catalog No. PIPA5144028 Supplier Invitrogen™ Supplier No. PA5144028

Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human MCF-7 whole cell, human A549 whole cell. IHC: mouse brain tissue, rat brain tissue, human breast cancer tissue, human lienal pupture tissue, human lung cancer tissue, human tonsil tissue, human renal cancer tissue, human liver tissue. ICC/IF: A549 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.

Specifications

• Antigen: PSMD8
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: PSMD8
• Gene Accession No.: P48556, Q9CX56
• Gene Alias: 26S proteasome non-ATPase regulatory subunit 8; 26S proteasome regulatory subunit p31; 26S proteasome regulatory subunit RPN12; 26S proteasome regulatory subunit S14; 6720456J22Rik; AA407360; AL033291; AL033322; AL033323; C76433; epididymis secretory sperm binding protein Li 91n; HEL-S-91n; HIP6; HYPF; Nin1p; p31; proteasome (prosome, macropain) 26S subunit, non-ATPase, 8; proteasome 26S non-ATPase subunit 8; proteasome 26S subunit, non-ATPase 8; proteasome 26S subunit, non-ATPase, 8; Psmd8; Rpn12; S14
• Gene Symbols: PSMD8
• Host Species: Rabbit
• Immunogen: E.coli-derived human PSMD8 recombinant protein (Position: A86-V350).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 292766, 5714, 57296
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG