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Invitrogen™ PSMF1 Polyclonal Antibody
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Catalog No. PIPA583537
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100 μL
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PIPA583537 100 μL
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Catalog No. PIPA583537 Supplier Invitrogen™ Supplier No. PA583537
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SSMILNVLEY GSQQVADLTL NLDDYIDAEH LGDFHRTYKN SEELRSRIVS GIITPIHEQW EKANVSSP Highest antigen sequence indentity to the following orthologs: Mouse - 82%, Rat - 82%.

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSMF1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PSMF1
Gene Accession No. Q92530
Gene Alias AW048666; BC012260; hPI31; PI31; proteasome (prosome, macropain) inhibitor subunit 1; proteasome (prosome, macropain) inhibitor subunit 1 (PI31); proteasome inhibitor PI31 subunit; proteasome inhibitor subunit 1; PSMB2; Psmf1; RP23 402M7.5; RP4 545L17.1; RP4-545L17.1
Gene Symbols PSMF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PSMF1. Recombinant protein control fragment (Product #RP-99413).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9491
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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