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Tocris Bioscience™ Psoralen-triethylene glycol azide
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Catalog No. 68625
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68-625 5 mg
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Catalog No. 68-625 Supplier Tocris Bioscience™ Supplier No. 6862/5
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RNA conformation probe; reagent for COMRADES RNA platform

Psoralen TEG Azide is used to probe RNA structure and conformation in live cells, using the cross-linking of matched RNAs and deep sequencing or COMRADES method. Psoralen crosslinks the RNA and the azide enables subsequent click reaction with biotin. The COMRADES method has been used to determine the architecture of the Zika virus RNA genome inside cells, and identified multiple site-specific interactions with human noncoding RNAs. It has also been used to map RNA-RNA interactions along the SARS-CoV-2 genome and subgenomes inside cells. Psoralen TEG Azide is cell permeable. For detailed methods please see references section below.

Specifications

Chemical Name or Material 3-(13-Azido-5,8,11-trioxa-2-azatridec-1-yl)-2,5,9-trimethyl-7 H-furo[3,2-g][1 ]benzopyran-7-one
CAS 1352815-11-2
Quantity 5 mg
Target DNA, RNA and Protein Synthesis Compounds
Molecular Formula C23H30N4O6
Purity 0.98
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