Invitrogen™ PSRC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102785

Catalog No. PIPA5102785

Description

Antibody detects endogenous levels of total PSRC1.

PSRC1 is required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.

Specifications

• Antigen: PSRC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSRC1
• Gene Alias: 5430413I02Rik; AL033312; Dda3; differential display and activated by p53; FP3214; MGC1780; OTTHUMP00000013785; OTTHUMP00000013786; p53-regulated DDA3; proline and serine rich coiled-coil 1; proline/serine-rich coiled-coil 1; proline/serine-rich coiled-coil protein 1; Psrc1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 691380, 84722
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q3KR66, Q6PGN9
• Gene Symbols: PSRC1
• Immunogen: A synthesized peptide derived from human PSRC1(Accession Q6PGN9), corresponding to amino acid residues S275-V325.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov