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Invitrogen™ PSRC1 Polyclonal Antibody
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Catalog No. PIPA596339
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100 μL
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PIPA596339 100 μL
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Catalog No. PIPA596339 Supplier Invitrogen™ Supplier No. PA596339
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MEDLEEDVRF IVDETLDFGG LSPSDSREEE DITVLVTPEK PLRRGLSHRS DPNAVAPAPQ GVRLSLGPLS PEKLEEILDE ANRLAAQLEQ CALQDRESAG EGLGPRRVKP SPRRETFVLK DSPVRDLLPT VNSLTRSTPS PSSLTPRLRS NDRKGSVRAL RATSGKRPSN MKRESPTCNL FPASKSPASS PLTRSTPPVR GRAGPSGRAA ASEET; Positive Samples: MCF7, HepG2, 293T; Cellular Location: Cytoplasm, cytoskeleton, spindle, spindle pole.

PSRC1 is required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSRC1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.32 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PSRC1
Gene Accession No. Q6PGN9
Gene Alias 5430413I02Rik; AL033312; Dda3; differential display and activated by p53; FP3214; MGC1780; OTTHUMP00000013785; OTTHUMP00000013786; p53-regulated DDA3; proline and serine rich coiled-coil 1; proline/serine-rich coiled-coil 1; proline/serine-rich coiled-coil protein 1; Psrc1
Gene Symbols PSRC1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human PSRC1 (NP_0010052901).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84722
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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