Invitrogen™ PTCH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA14135

Catalog No. PA14135

Description

PA1-4135 detects Patched 2 (PTCH2) in human and mouse samples. PA1-4135 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~158 kDa protein representing PTCH2 in fetal brain lysate. The PA1-4135 immunogen is a synthetic peptide corresponding to residues G(226) P F A S L E G F R(235) of human PTCH2.

Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.

Specifications

• Antigen: PTCH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTCH2
• Gene Alias: patched 2; patched homolog 1; patched homolog 2; protein patched homolog 2; PTC2; Ptch1; PTCH2; RP11-269F19.8; UNQ560/PRO1121/PRO57079
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19207, 8643
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O35595, Q9Y6C5
• Gene Symbols: PTCH2
• Immunogen: Synthetic peptide corresponding to residues G(226) P F A S L E G F R(235) of human PTCH2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG