Invitrogen™ PTF1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578664

Catalog No. PIPA578664

Description

Positive Control: AsPC-1 Predicted Reactivity: Mouse (96%), Rat (95%), Zebrafish (86%), Xenopus laevis (81%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PFT1A is a component of the pancreas transcription factor 1 complex and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.

Specifications

• Antigen: PTF1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTF1A
• Gene Alias: bHLH transcription factor; bHLH transcription factor p48; BHLHA29; class A basic helix-loop-helix protein 29; class II bHLH protein PTF1A; exocrine pancreas-specific transcription factor p48; p48 DNA-binding subunit of transcription factor PTF1; PACA; PAGEN2; pancreas associated transcription factor 1a; pancreas specific transcription factor, 1a; pancreas transcription factor 1 subunit alpha; pancreas transcription factor1 p48 subunit; pancreas-specific transcription factor 1a; PTF1; PTF1A; PTF1p48; PTF1-p48; Ptfa; si:zc142h2.2; zgc:112216
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 256297
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q7RTS3
• Gene Symbols: PTF1A
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human PTF1A. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov