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Invitrogen™ PTGES2 Polyclonal Antibody
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Catalog No. PIPA564984
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100 μL
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PIPA564984 100 μL
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Catalog No. PIPA564984 Supplier Invitrogen™ Supplier No. PA564984
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AQDLHAERSAA QLSLSSRLQL TLYQYKTCPF CSKVRAFLDF HALPYQVVEV NPVRRAEIKF SSYRKVPILV AQEGESSQ Highest antigen sequence identity to the following orthologs - mouse 89%, rat 91%.

The PTGES2 gene encodes for the enzyme prostaglandin E synthase 2 (PTGES2), which is crucial for the biosynthesis of prostaglandin E2 (PGE2) from arachidonic acid. This enzyme operates downstream of the cyclooxygenase (COX) pathway, particularly interacting with COX-1 and COX-2 enzymes. PTGES2 is involved in various physiological and pathological processes by generating PGE2, which functions in inflammation, fever generation, and pain. Notably, PTGES2 is a membrane-associated protein and is distinct in its role compared to other prostaglandin synthases due to its specific functional and regulatory properties. Its activity is essential in fine-tuning the levels of PGE2 in tissues, impacting numerous signaling cascades, including those involved in immune responses and vascular functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTGES2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ptges2
Gene Accession No. Q9H7Z7
Gene Alias 0610038H10Rik; C79137; C9orf15; FLJ14038; gamma-interferon-activated transcriptional element-binding factor 1; GATE-binding factor 1; Gbf1; GBF-1; membrane-associated prostaglandin E synthase 2; membrane-associated prostaglandin E synthase-2; MGC11289; Microsomal prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; mPGE synthase-2; Mpges2; mPGES-2; PGES2; Prostaglandin E synthase 2; Prostaglandin E synthase 2 truncated form; Prostaglandin-H(2) E-isomerase; PTGES2; RP11-395P17.2
Gene Symbols Ptges2
Host Species Rabbit
Immunogen Recombinant Human PTGES2. Recombinant protein control fragment (Product #RP-104567).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80142
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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