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Invitrogen™ PTGIS Polyclonal Antibody
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Catalog No. PIPA553132
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100 μL
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PIPA553132 100 μL
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Catalog No. PIPA553132 Supplier Invitrogen™ Supplier No. PA553132
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LTLYGIEALP RTHESQAQDR VHSADVFHTF RQLDRLLPKL ARGSLSVGDK DHMCSVKSRL WKLLSPARLA RRAHRSKWLE SYLLHLEEMG VSEEMQARAL VLQLWATQGN MGPAAFWLLL FLLKNPEALA AVRGELESIL WQAEQ Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 85%.

CYP8A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTGIS
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PTGIS
Gene Accession No. Q16647
Gene Alias Cyp8; CYP8A1; cytochrome P450 8A1; cytochrome P450, family 8, subfamily A, polypeptide 1; hydroperoxy icosatetraenoate dehydratase; LOW QUALITY PROTEIN: prostacyclin synthase; MGC126858; MGC126860; PGIS; Prostacyclin synthase; prostaglandin I2 (prostacyclin) synthase; prostaglandin I2 (prostacyclin) synthase like; prostaglandin I2 synthase; PTGI; ptgis; ptgisl
Gene Symbols PTGIS
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PTGIS. Recombinant protein control fragment (Product #RP-90174).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5740
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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