Invitrogen™ PTGR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA598100

Catalog No. PIPA598100

Description

PTGR2 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

ZADH1 (zinc binding alcohol dehydrogenase, domain containing 1), also known as PTGR2 (prostaglandin reductase 2), PGR2 or 15-oxoprostaglandin 13-reductase, is a 351 amino acid cytoplasmic protein that belongs to the NADP-dependent oxidoreductase L4BD family. Functioning as s a 15-oxoprostaglandin 13-reductase, ZADH1 catalyzes the conversion of 15-keto-prostaglandin E2 to 15-keto-13, 14-dihydro-prostaglandin E2 in a NADPH-dependent manner. ZADH1 overexpression has been found to repress PPAR gamma transcriptional activity and adipocyte differentiation. Widely expressed, ZADH1 is found at highest levels in heart, kidney, liver, pancreas and prostate, with moderate levels found in brain, small intestine, lung, testis and skeletal muscle. ZADH1 exists as a monomer, utilizes NADPH as a cofactor, and undergoes alternative splicing to produce two isoforms that are encoded by a gene located on human chromosome 14q24.3.

Specifications

• Antigen: PTGR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTGR2
• Gene Alias: 15-oxoprostaglandin 13-reductase; 15-oxoprostaglandin 13-reductase {ECO:0000250; 15-oxoprostaglandin-delta13-reductase; 1810016I24Rik; 9130222H03Rik; 9630002F03Rik; AI838763; B830026H24Rik; epididymis secretory protein Li 298; HEL-S-298; PGR2; PGR-2; PRG2; PRG-2; PRG-2 {ECO:0000250; prostaglandin reductase 2; prostaglandin reductase 2 {ECO:0000250; PTGR2; ptgr2 {ECO:0000250; UniProtKB:Q8VDQ1}; ZADH1; zinc binding alcohol dehydrogenase, domain containing 1; zinc-binding alcohol dehydrogenase domain-containing protein 1
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 145482
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 3.1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q8N8N7
• Gene Symbols: PTGR2
• Immunogen: Recombinant Human Prostaglandin reductase 2 protein (206-282AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG