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Invitrogen™ PTGR2 Polyclonal Antibody
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Catalog No. PIPA5143285
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100 μg
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PIPA5143285 100 μg
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Catalog No. PIPA5143285 Supplier Invitrogen™ Supplier No. PA5143285
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

ZADH1 (zinc binding alcohol dehydrogenase, domain containing 1), also known as PTGR2 (prostaglandin reductase 2), PGR2 or 15-oxoprostaglandin 13-reductase, is a 351 amino acid cytoplasmic protein that belongs to the NADP-dependent oxidoreductase L4BD family. Functioning as s a 15-oxoprostaglandin 13-reductase, ZADH1 catalyzes the conversion of 15-keto-prostaglandin E2 to 15-keto-13, 14-dihydro-prostaglandin E2 in a NADPH-dependent manner. ZADH1 overexpression has been found to repress PPAR gamma transcriptional activity and adipocyte differentiation. Widely expressed, ZADH1 is found at highest levels in heart, kidney, liver, pancreas and prostate, with moderate levels found in brain, small intestine, lung, testis and skeletal muscle. ZADH1 exists as a monomer, utilizes NADPH as a cofactor, and undergoes alternative splicing to produce two isoforms that are encoded by a gene located on human chromosome 14q24.3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTGR2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene PTGR2
Gene Accession No. 0
Gene Alias 15-oxoprostaglandin 13-reductase; 15-oxoprostaglandin 13-reductase {ECO:0000250; 15-oxoprostaglandin-delta13-reductase; 1810016I24Rik; 9130222H03Rik; 9630002F03Rik; AI838763; B830026H24Rik; epididymis secretory protein Li 298; HEL-S-298; PGR2; PGR-2; PRG2; PRG-2; PRG-2 {ECO:0000250; prostaglandin reductase 2; prostaglandin reductase 2 {ECO:0000250; PTGR2; ptgr2 {ECO:0000250; UniProtKB:Q8VDQ1}; ZADH1; zinc binding alcohol dehydrogenase, domain containing 1; zinc-binding alcohol dehydrogenase domain-containing protein 1
Gene Symbols PTGR2
Host Species Goat
Immunogen Peptide with sequence C-PDNINEGQVQVRT (aa 31-43).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100156930
Target Species Pig
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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