PTGS2 Mouse anti-Human, Clone: OTI10H5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF805307

Catalog No. 50-166-7368

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Specifications

• Antigen: PTGS2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: PTGS2
• Gene Alias: COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5743
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI10H5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P35354
• Gene Symbols: PTGS2
• Immunogen: Human recombit protein fragment corresponding to amino acids 18-260 of human PTGS2 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a