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  6. PTH Antibody (PTH/1175) - C-terminus, R&D Systems™

PTH Antibody (PTH/1175) - C-terminus, R&D Systems™
SDP

Catalog No. NBP24511501
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NBP24511501 0.1 mg
NBP24511500 0.02 mg
NBP24511502 0.2 mg
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Catalog No. NBP24511501 Supplier R&D Systems Supplier No. NBP2451150.1MG

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Description

A Novus product, part of R&D Systems. Mouse Monoclonal Antibody

PTH Monoclonal specifically detects PTH in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).

Specifications

Antigen PTH
Applications Immunohistochemistry
Classification Monoclonal
Clone PTH/1175
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P01270
Gene Alias Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1
Gene Symbols PTH
Host Species Mouse
Immunogen Recombinant fragment (84 amino acid residues from C-terminus) of human PTH protein
Molecular Weight of Antigen 9 kDa
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Apoptosis, Cancer
Primary or Secondary Primary
Gene ID (Entrez) 5741
Test Specificity Epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Target Species Human
Content And Storage Store at 4C.
Product Type Antibody
Form Purified
Isotype IgG2b κ
Product Line Novus
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