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Invitrogen™ PTHLH Polyclonal Antibody
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Catalog No. PIPA557493
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100 μL
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PIPA557493 100 μL
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Catalog No. PIPA557493 Supplier Invitrogen™ Supplier No. PA557493
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KRAVSEHQLL HDKGKSIQDL RRRFFLHHLI AEIHTAEIRA TSEVSPNSKP SPNTKNHPVR FGSDDEGRYL TQETNKVETY KEQPLKTPGK KKKGKPGKRK EQEKKKRRTR SAWLDSGVTG SGL Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 24%.

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTHLH
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PTHLH
Gene Accession No. P12272
Gene Alias BDE2; calciotropic hormone, growth factor; HHM; osteostatin; parathyroid hormone like hormone; parathyroid hormone related peptide; parathyroid hormone-like hormone; parathyroid hormone-like hormone preproprotein; parathyroid hormone-like peptide; parathyroid hormone-like protein; parathyroid hormone-like related protein; parathyroid hormone-related peptide; parathyroid hormone-related protein; parathyroid-like peptide; PLP; PTHLH; PTH-like; PTHR; PTH-related peptide; PTH-related protein; Pthrp; PTH-rP; PTHrP[107-139]; PTHrP[1-36]; PTHrP[38-94]
Gene Symbols PTHLH
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PTHLH. Recombinant protein control fragment (Product #RP-89708).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5744
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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