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Invitrogen™ PTMA Polyclonal Antibody
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Catalog No. PIPA571580
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Quantity:
400 μL
Catalog No. Quantity
PIPA571580 400 μL
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Catalog No. PIPA571580

Supplier: Invitrogen™ PA571580

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Description

Rabbit Polyclonal Antibody

PTMA Polyclonal Antibody for Western Blot, IHC (P), Flow

The thymus gland produces several hormones or hormone-like substances which are derived from a polypeptide precursor containing (in the rat) 113 amino acids and known as prothymosin-alpha. A peptide containing 28 amino acid residues, named thymosin-alpha-1, was originally isolated from calf thymosin fraction 5 and shown to restore various aspects of immune function in several in vitro and invivo test systems. Thymosin-alpha-1 was subsequently isolated from a similar fraction from human thymosin and reported to have the same amino acid sequence as bovine thymosin-alpha-1. In 2003, Jiang et al. identified a pathway that regulates mitochondria-initiated caspase activity. In this pathway, putative human HLA class II-associated protein (PHAP) promoted caspase-9 activation after apoptosome formation, whereas prothymosin-alpha-1 negatively regulated caspase-9 activation by inhibiting apoptosome formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTMA
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene PTMA
Gene Accession No. P06454
Gene Alias alpha-prothymosin; gene sequence 28; prothymosin alpha; prothymosin alpha protein; Prothymosin alpha, N-terminally processed; prothymosin, alpha; prothymosin-alpha; PTMA; Thym; thymosin; Thymosin alpha; Thymosin alpha-1; TMSA; TMSB4; TMSB4X
Gene Symbols PTMA
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 1-31 amino acids from the N-terminal region of human PTMA.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5757
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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