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PTOP Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988044
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100 μL
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50-198-8044 100 μL
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Catalog No. 50-198-8044 Supplier Bioss Supplier No. BS7825R
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Rabbit Polyclonal Antibody

This gene encodes a uridine 5′ -monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5′ -monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5′ -monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Specifications

Antigen PTOP
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ACD
Gene Accession No. Q96AP0
Gene Alias ACD; ACD, shelterin complex subunit and telomerase recruitment factor; adrenocortical dysplasia; adrenocortical dysplasia homolog; adrenocortical dysplasia homolog (mouse); Adrenocortical dysplasia protein; Adrenocortical dysplasia protein homolog; BOS_17241; PIP1; POT1 and TIN2-interacting protein; PTOP; TIN2 interacting protein 1; TINT1; TPP 1; TPP I; TPP1; TPPI
Gene Symbols ACD
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PTOP.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 65057
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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