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Invitrogen™ PTP1B Monoclonal Antibody (OTI1A2)
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Catalog No. PIMA525574
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Quantity:
100 μL
Catalog No. Quantity
PIMA525574 100 μL
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Catalog No. PIMA525574

Supplier: Invitrogen™ MA525574

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Description

Mouse Monoclonal Antibody

PTP1B Monoclonal Antibody for Western Blot, ICC/IF, Flow

PTP1B (PTPN1) is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK and in turn inactivates the protein kinase activity of EIF2AK3/PERK. PTP1B also plays a role in CKII- and p60c-src-induced signal transduction cascades. It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. PTP1B also regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTP1B
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone OTI1A2
Concentration 0.72 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PTPN1
Gene Accession No. P18031
Gene Alias CPTP1; EC 3.1.3.48; EGK_02300; hgnc9642; KIAA0283; protein tyrosine phosphatase 1B; protein tyrosine phosphatase non-receptor type 1; protein tyrosine phosphatase, non-receptor type 1; protein tyrosine phosphatase, placental; protein-protein-tyrosine phosphatase HA2; protein-tyrosine phosphatase 1B; Protein-tyrosine phosphatase HA2; PTN1; Ptp; PTP1B; PTP-1B; ptp1b protein; PTP-HA2; Ptpn1; RP5-1121H13.2; RPTPrho; tyrosine phosphatase 1b; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 1; wu:fk54h03
Gene Symbols PTPN1
Host Species Mouse
Immunogen Full length human recombinant protein of PTPN1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5770
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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