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Invitrogen™ PTP1B Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA587246
Description
Purity is > 95% by SDS-PAGE.
PTP1B (PTPN1) is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK and in turn inactivates the protein kinase activity of EIF2AK3/PERK. PTP1B also plays a role in CKII- and p60c-src-induced signal transduction cascades. It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. PTP1B also regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Specifications
PTP1B | |
Polyclonal | |
Unconjugated | |
PTPN1 | |
CPTP1; EC 3.1.3.48; EGK_02300; hgnc9642; KIAA0283; protein tyrosine phosphatase 1B; protein tyrosine phosphatase non-receptor type 1; protein tyrosine phosphatase, non-receptor type 1; protein tyrosine phosphatase, placental; protein-protein-tyrosine phosphatase HA2; protein-tyrosine phosphatase 1B; Protein-tyrosine phosphatase HA2; PTN1; Ptp; PTP1B; PTP-1B; ptp1b protein; PTP-HA2; Ptpn1; RP5-1121H13.2; RPTPrho; tyrosine phosphatase 1b; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 1; wu:fk54h03 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
19246, 24697, 5770 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
P18031, P20417, P35821 | |
PTPN1 | |
Recombinant full length Human PTPN1. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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