Invitrogen™ PTPMT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533007

Catalog No. PIPA533007

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Dog, Panda (100%); Marmoset, Bovine, Pig (88%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells.

Specifications

• Antigen: PTPMT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTPMT1
• Gene Alias: 1110001D10Rik; 2810004N20Rik; DUSP23; MOSP; NB4 apoptosis/differentiation related protein; phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Phosphoinositide lipid phosphatase; Plip; PNAS-129; protein tyrosine phosphatase, mitochondrial 1; protein-tyrosine phosphatase mitochondrial 1; PTEN-like phosphatase; PTPMT1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114971, 483622
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q8WUK0
• Gene Symbols: PTPMT1
• Immunogen: Synthetic 16 amino acid peptide from N-terminus of human PTPMT1.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Canine, Monkey
• Product Type: Antibody
• Isotype: IgG