PTPN11 Mouse anti-Human, Clone: OTI1F7, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA501914

Catalog No. 50-167-3015

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noo syndrome as well as acute myeloid leukemia.

Specifications

• Antigen: PTPN11
• Classification: Monoclonal
• Concentration: 0.86 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q06124
• Gene Symbols: PTPN11
• Immunogen: Full length human recombit protein of human PTPN11 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: OTI1F7
• Conjugate: Unconjugated
• Gene: PTPN11
• Gene Alias: BPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5781
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid