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PTPN11 Mouse anti-Human, Clone: OTI1F7, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA501914
Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noo syndrome as well as acute myeloid leukemia.Specifications
PTPN11 | |
Monoclonal | |
0.86 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
Q06124 | |
PTPN11 | |
Full length human recombit protein of human PTPN11 produced in HEK293T cell. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Flow Cytometry, Western Blot | |
OTI1F7 | |
Unconjugated | |
PTPN11 | |
BPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2 | |
Mouse | |
Affinity Chromatography | |
RUO | |
5781 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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