PTPN11 Mouse anti-Human, Mouse, Rat, Clone: 3F8A8, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 667951IG150UL

Catalog No. 50-173-7195

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noo syndrome as well as acute myeloid leukemia.

Specifications

• Antigen: PTPN11
• Classification: Monoclonal
• Concentration: 0.8 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P35235, P41499, Q06124
• Gene Symbols: PTPN11
• Immunogen: PTPN11 Fusion Protein Ag13649
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 3F8A8
• Conjugate: Unconjugated
• Gene: PTPN11
• Gene Alias: BPTP3, CFC, NS1, PTP 1D, PTP 2C, PTP2C, PTPN11, SH PTP2, SH PTP3, SHP 2, SHP2, SHPTP2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 19247, 25622, 5781
• Content And Storage: -20°C
• Form: Liquid