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PTPN12 Recombinant Rabbit Monoclonal Antibody (BL-5-2F8), Bethyl Laboratories
Rabbit Recombit Monoclonal Antibody
$157.08 - $378.84
Specifications
| Antigen | PTPN12 |
|---|---|
| Clone | BL-5-2F8 |
| Applications | Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Classification | Recombinant Monoclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-157-1268
|
Bethyl Laboratories, Inc
A700007T |
20 μL |
Each for $157.08
|
|
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|
50-157-1267
|
Bethyl Laboratories, Inc
A700007 |
100 μL |
Each for $378.84
|
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Description
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections. For IHC, epitope retrieval with citrate buffer pH 6.0 is recommende
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms.Specifications
| PTPN12 | |
| Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human | |
| Q05209 | |
| 5782 | |
| Between 499 and 780 | |
| Primary | |
| 4° C | |
| PTPN12 |
| BL-5-2F8 | |
| Recombinant Monoclonal | |
| Liquid | |
| RUO | |
| BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2 | |
| tcag7.1075, PTP-PEST, PTPG1 | |
| PTPN12 | |
| IgG | |
| Ion-exchange chromatography | |
| Antibody |
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