PTPN7 Monoclonal Antibody (OTI3B10), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA503714

Catalog No. 50-167-4541

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PTPN7
• Classification: Monoclonal
• Concentration: 0.72 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P35236, P49445, Q8BUM3
• Gene Symbols: Ptpn7
• Immunogen: Full length human recombit protein of human PTPN7 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI3B10
• Conjugate: Unconjugated
• Gene: PTPN7
• Gene Alias: BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 246781, 320139, 5778, 607227
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid