PTPN7 Monoclonal Antibody (OTI3B10), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-4541	100 μL
50-254-0745	30 μL

Catalog No. 50-167-4541 Supplier OriGene Supplier No. TA503714

Description

Mouse Monoclonal Antibody

The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PTPN7
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: OTI3B10
• Concentration: 0.72 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: PTPN7
• Gene Accession No.: P35236, P49445, Q8BUM3
• Gene Alias: BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI
• Gene Symbols: Ptpn7
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human PTPN7 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 246781, 320139, 5778, 607227
• Target Species: Canine, Human, Mouse, Rat
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b