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Invitrogen™ PTPN7 Polyclonal Antibody
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Catalog No. PIPA553927
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100 μL
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PIPA553927 100 μL
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Catalog No. PIPA553927 Supplier Invitrogen™ Supplier No. PA553927
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LIVMLTQLRE GKEKCVHYWP TEEETYGPFQ IRIQDMKECP EYTVRQLTIQ YQEERRSVKH ILFSAWPDHQ TPESAGPLLR LVAEVEESPE TAAHPGPIVV HCSAGIGRTG CFIATRIGCQ QLKARGEVDI LGIVCQL Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.

The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPN7
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PTPN7
Gene Accession No. P35236
Gene Alias BPTP-4; C920001D21Rik; dual specificity phosphatase 1; hematopoietic protein-tyrosine phosphatase; HEPTP; Lcptp; LC-PTP; LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 7; LPTP; protein tyrosine phosphatase non-receptor type 7; protein tyrosine phosphatase, non-receptor type 7; protein tyrosine phosphatase, non-receptor type 7 isoform 2; protein-tyrosine phosphatase LC-PTP; protein-tyrosine phosphatase, non-receptor type 7; protein-tyrosine phosphatase, nonreceptor-type, stress induced; Ptpn7; PTPNI; tyrosine-protein phosphatase non-receptor type 7
Gene Symbols PTPN7
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PTPN7. Recombinant protein control fragment (Product #RP-91566).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5778
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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