Invitrogen™ PTPN7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570547

Catalog No. PIPA570547

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 77%.

The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PTPN7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTPN7
• Gene Alias: BPTP-4; C920001D21Rik; dual specificity phosphatase 1; hematopoietic protein-tyrosine phosphatase; HEPTP; Lcptp; LC-PTP; LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 7; LPTP; protein tyrosine phosphatase non-receptor type 7; protein tyrosine phosphatase, non-receptor type 7; protein tyrosine phosphatase, non-receptor type 7 isoform 2; protein-tyrosine phosphatase LC-PTP; protein-tyrosine phosphatase, non-receptor type 7; protein-tyrosine phosphatase, nonreceptor-type, stress induced; Ptpn7; PTPNI; tyrosine-protein phosphatase non-receptor type 7
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 246781
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P49445
• Gene Symbols: PTPN7
• Immunogen: synthetic peptide directed towards the middle region of rat PTPN7.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG