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Invitrogen™ PTPRB Monoclonal Antibody (2-A2)
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Catalog No. PIMA532904
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Quantity:
100 μL
Catalog No. Quantity
PIMA532904 100 μL
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Catalog No. PIMA532904

Supplier: Invitrogen™ MA532904

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Description

Mouse Monoclonal Antibody

PTPRB Monoclonal Antibody for ICC/IF

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRB
Applications Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone 2-A2
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene PTPRB
Gene Accession No. B2RU80, P23467
Gene Alias 3230402H02Rik; C130094E24; HPTPB; HPTP-BETA; protein tyrosine phosphatase, receptor type B; protein tyrosine phosphatase, receptor type, B; protein tyrosine phosphatase, receptor type, beta polypeptide; protein-tyrosine phosphatase beta; PTPB; Ptprb; Ptpz; receptor-type tyrosine-protein phosphatase beta; Rptpb; R-PTP-BETA; vascular endothelial protein tyrosine phosphatase; VEPTP; VE-PTP
Gene Symbols PTPRB
Host Species Mouse
Immunogen Recombinant protein within Human PTPRB aa 1,018-1,161.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19263, 5787
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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