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Invitrogen™ PTPRB Polyclonal Antibody
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Catalog No. PIPA568309
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100 μL
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PIPA568309 100 μL
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Catalog No. PIPA568309 Supplier Invitrogen™ Supplier No. PA568309
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Description

Rabbit Polyclonal Antibody

PTPRB Polyclonal Antibody for Western Blot

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTPRB
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PTPRB
Gene Accession No. P23467
Gene Alias 3230402H02Rik; C130094E24; HPTPB; HPTP-BETA; protein tyrosine phosphatase, receptor type B; protein tyrosine phosphatase, receptor type, B; protein tyrosine phosphatase, receptor type, beta polypeptide; protein-tyrosine phosphatase beta; PTPB; Ptprb; Ptpz; receptor-type tyrosine-protein phosphatase beta; Rptpb; R-PTP-BETA; vascular endothelial protein tyrosine phosphatase; VEPTP; VE-PTP
Gene Symbols PTPRB
Host Species Rabbit
Immunogen Synthesized peptide derived from human PTPRB.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5787
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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